Life Sciences

CIP/SIP

CIP/SIP Systems are designed for purification and sterilization of pharmaceutical units, systems and single components.

We have done good number of CIP/SIP system automation for our clients.

Printing Process Of CIP/SIP Machine

“We have developed the printing mechanism for the complete process through the HMI using MicroLogix 1400 PLC (Allen Bradley) & Panel View Plus 600 (Allen Bradley) hardware & RSLogix 500 software. ”.

Challenge

To print the machine actual working process step by step by keeping the print of all related parameters being taken into effect as per their required set points through the HMI without any time delay .

Solution

We have developed the application as strictly according to the working mechanism of the machine with each change of phase is being printed and specified on the print as required without any time delay. Even the phase changes in the process with milliseconds gap is printed as per the conditions of the working of machine.

What is CIP/SIP?

Clean-in-Place (CIP) is a method of cleaning the interior surfaces of pipes, vessels, process equipment, filters and associated fittings, without disassembly. The benefit to industries that use CIP is that the cleaning is faster, less labor intensive and more repeatable, and poses less of a chemical exposure risk to people. CIP started as a manual practice involving a balance tank, centrifugal pump, and connection to the system being cleaned.CIP has evolved to include fully automated systems with programmable logic controllers, multiple balance tanks, sensors, valves, heat exchangers, data acquisition and specially designed spray nozzle systems. Simple, manually operated CIP systems can still be found in use today. The Steam-In-Place (SIP) System is responsible for repeatedly steaming areas of product contact, including vessels, flow paths, and sample ports. This may be done to reduce the bio-burden on the system, or to kill harmful materials at the end of a batch. A typical SIP system will ensure that all areas being steamed have been exposed to live steam for an adequate time to ensure the desired “kill”effect.The steam system must be able to measure and control steam temperature, pressure, and/or flow to ensure adequate steaming. Calculation of Fahrenheit or other measures is often required to meet process needs.

System Configuration and Implementation

The system has the two micrologix 1400 plc’ whose data is shared over the Modbus RTU through messaging to the main control panel PLC. PVP600 (HMI) is used to Operate the system and to print the process. Previously the system is running the printer through the plc serial port. But due to the insufficient memory no editing to the process and print is possible and this is the major challenge during the application development. And this is the reason why we choose to print the process through HMI as it facilitates us to develop the application with almost zero use of memory of PLC and logic correction to process as required by making the memory free.

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